Using Dermatoscopy to Identify and Differentiate Between Acute and Chronic Inflammatory and Allergic Skin Conditions

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dc.creatorDavlat ugli, Abdullaev Sulton
dc.creatorUktamjon ugli, Toshev Suhrob
dc.creatorDavlatovich, Abdullaev Xasan
dc.creatorBahodirovich, Tillakobilov Ismoil
dc.date2023-06-28
dc.date.accessioned2023-08-21T09:09:27Z
dc.date.available2023-08-21T09:09:27Z
dc.descriptionTopical glucocorticosteroid facilities (TGKS) were first introduced in clinical dermatological practice in the early 1950s, revolutionizing the treatment of inflammatory skin diseases. Today, they remain the leading treatment method for the most common dermatoses. The mechanism of action of topical corticosteroids is complex. The glucocorticosteroid hormone penetrates the nuclei of epidermal cells, enhancing the synthesis of lipocortins that inhibit the activity of phospholipase A2, leading to a decrease in the production of inflammatory mediators such as prostaglandins, leukotrienes, and thromboxanes, as well as a reduction in the number of antigen-presenting and mast cells. TGKS slows down the synthesis of glycosaminoglycans, collagen, and elastin, reduces the release of histamine and other pro-inflammatory mediators, and reduces the activity of Langerhans cells. Additionally, TGCS inhibits the synthesis of nucleic acids in immunocompetent cells and fibroblasts in the basal layer of the epidermis, contributing to a local immunosuppressive effect.en-US
dc.formatapplication/pdf
dc.identifierhttps://univerpubl.com/index.php/woscience/article/view/2237
dc.identifier.urihttp://dspace.umsida.ac.id/handle/123456789/23087
dc.languageeng
dc.publisherUniver Publen-US
dc.relationhttps://univerpubl.com/index.php/woscience/article/view/2237/1948
dc.sourceWorld of Science: Journal on Modern Research Methodologies; Vol. 2 No. 6 (2023): World of Science: Journal on Modern Research Methodologies; 93-101en-US
dc.source2835-3072
dc.subjectdermoscopic paintingen-US
dc.subjecttreatmenten-US
dc.subjectallergic dermatosesen-US
dc.titleUsing Dermatoscopy to Identify and Differentiate Between Acute and Chronic Inflammatory and Allergic Skin Conditionsen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Articleen-US
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World of Science: Journal on Modern Research Methodologies