ASSOCIATION OF CARDIOVASCULAR COMPLICATIONS AND NONALCOHOLIC FATTY LIVER DISEASE

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dc.creatorD. A., Parpibaeva
dc.creatorU. V, Turbanova
dc.creatorN. T, Buvamukhamedova
dc.creatorG. P, Mirzayeva
dc.creatorY. I., Nadirova
dc.date2023-06-08
dc.date.accessioned2023-08-21T09:08:24Z
dc.date.available2023-08-21T09:08:24Z
dc.descriptionThe presented review article analyzes the pathogenetic mechanisms of cardiovascular disease (CVD) formation in patients with nonalcoholic fatty liver disease (NAFLD). The role of insulin resistance, proinflammatory cytokines, adipocytokines, genetic factors of atherosclerosis formation, diastolic left ventricular dysfunction and chronic heart failure was considered. It was noted that ectopic accumulation of adipose tissue can be a key pathogenetic element of CVDs formation, and, therefore, NAFLD patients have a high risk of their development. It has been shown that people with NAFLD and higher levels of C-reactive protein have the highest risk of CVD formation. It was demonstrated that the degree of histological changes in the liver in NAFLD patients correlated with the manifestations of atherosclerotic changes in the carotid arteries. It was shown that the increased level of transaminases in NAFLD patients was an independent risk factor of cardiac insufficiency formation. It was noted that echocardiographic signs of sclerotic changes of aortic valve have a clear association with the presence of NAFLD in patients. It was shown that PNPLA3 GG genotype is associated with the severity of atherosclerotic changes in the carotid arteries in young patients with NAFLD.en-US
dc.formatapplication/pdf
dc.identifierhttps://univerpubl.com/index.php/horizon/article/view/1938
dc.identifier.urihttp://dspace.umsida.ac.id/handle/123456789/22853
dc.languageeng
dc.publisherUniversal Publishing INC.en-US
dc.relationhttps://univerpubl.com/index.php/horizon/article/view/1938/1690
dc.sourceHorizon: Journal of Humanity and Artificial Intelligence; Vol. 2 No. 6 (2023): Horizon: Journal of Humanity and Artificial Intelligence; 74-78en-US
dc.source2835-3064
dc.source2835-3064
dc.subjectnonalcoholic fatty liver diseaseen-US
dc.subjectinsulin resistanceen-US
dc.subjectrisken-US
dc.subjectcardiovascular diseaseen-US
dc.subjectatherosclerosisen-US
dc.titleASSOCIATION OF CARDIOVASCULAR COMPLICATIONS AND NONALCOHOLIC FATTY LIVER DISEASEen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Articleen-US
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